A clinical research study for agitation associated with Alzheimer's diseaseEnroll Now
The TRIAD Research Study is currently evaluating an investigational medication that may reduce symptoms of agitation due to Alzheimer's disease.
Agitation due to Alzheimer's disease can be extremely disruptive and potentially harmful to you and your loved one. Aggression, which can be both physical and verbal, plays a major role in agitation. Aggressive behaviors can make caring for your loved one intimidating and stressful. At this time, the FDA has not approved any medications to treat agitation in Alzheimer's disease.
Your loved one's participation could help advance new treatment options in the future for this difficult condition.
Agitation affects almost 4.3 million of the 5.4 million people with Alzheimer's disease.
Qualified participants will be required to attend 8 clinic visits over approximately 16 weeks with their caregiver. In addition to evaluations, each study visit will also provide an opportunity for the participant and caregiver to meet with the study team, address any questions they may have, and share their experiences.
Certain qualified paricipants may have an opportunity to receive the investigational medication for an additional year, as part of an extension study.
Alzheimer’s disease is a progressive disease that damages brain cells and impacts important mental functions such as memory, thinking, and behavior. As the brain cells deteriorate, memory and mental function steadily decline. People with Alzheimer’s disease may begin to exhibit behaviors that are not typical of their personality.
Common behaviors associated with agitation in Alzheimer’s disease are irritability, hostility, physical and verbal aggression, an uncooperative attitude, wandering, and pacing. Unpredictable outbursts can place additional strain on caregivers and diminish the quality of life for both caregivers and their loved ones.
Currently, there are no medications approved by the United States Food and Drug Administration (FDA) to treat agitation in Alzheimer's disease.
Caring for a loved one with agitation due to Alzheimer's disease can be a challenge. For more information about the condition and for additional caregiver resources please visit our Other Resources page.
If you would like to learn more about agitation in Alzheimer's disease, please visit:
The Alzheimer’s Foundation of America (AFA) has information about Alzheimer’s disease and agitation, as well as caregiving resources and support groups
The Alzheimer’s Association is the world’s leading health organization in Alzheimer's disease care, support, and research
Caring for a loved one with agitation due to Alzheimer’s disease can be challenging. If you are a caregiver seeking advice and resources, please visit:
The Caregiver Action Network (CAN) is dedicated to providing education, support, and resources to family caregivers
The Alzheimer’s Care Resource Center is committed to helping navigate the challenges of caring for someone with Alzheimer’s disease
Avanir provides links to third party resources for your convenience. None of these organizations endorse or are otherwise affiliated with Avanir or its products, including TRIAD. Additionally, these links connect to websites not owned or controlled by Avanir. Avanir is not responsible for such websites in any way, including the accuracy of their content, their data collection practices, or their privacy policies. We encourage you to evaluate any information or advice provided by any of these websites with your doctor. We also encourage you refrain from sharing any personal or private information with any website unless you are confident that you understand and are comfortable with its data collection practices and privacy policies.